I have a funny habit. I tend to use my mouse right-handed at home but left-handed at the office. I don’t do it annoy coworkers looking to use my computer (since I also switch the mouse button functions). That’s just an amusing side-effect. I do it because extend use of the mouse by my right hand causes me great pain.

I noticed that by switching over to my left hand has brought it back considerably and I rarely experience any discomfort on my right hand anymore when I use my mouse right-handed.

Listen to your body. If it’s broke, fix it.